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This is a Global community where you can read about, and provide your input or comments on, anything to do with Biocatalysis.
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In Memoriam, Professor Carlos F. Barbas III, PhD

August 18, 2014

In June, we lost a creative and prolific scientist in the field of Catalytic Antibodies and Chemocatalysis.  Professor Carlos F. Barbas of the The Scripps Research Institute passed away at the age of 49, after a fight with a rare form of thyroid cancer. A Memorial Symposium was held at Scripps last week, with scientific... Read More

Jim Lalonde (VP of Research & Development)

Enhanced Directed Evolution Of Enzymes

August 12, 2014

Directed evolution is a hugely powerful protein-engineering tool that is used in all manner of areas such as industry, medicine and agriculture. Directed evolution technologies have been critical in reducing the timescales and investment required for enzyme optimization programs. Other enzyme technologies are also being investigated for commercial manufacturing, as organizations look for further ways... Read More

Scientist at Codexis (Scientist)

Biochemistry Scientist at Codexis

Nanotechnology + Biocatalysis = Nanobiocatalysts

June 26, 2014

This week saw the second annual graphene summit hosted by the birthplace of graphene, the University of Manchester. For two days companies from all over the world gathered to discuss the applications and the future of graphene. The industry applications of biocatalysis however are well known. Both the pharmaceutical and fine chemicals industries have taken... Read More

Gabriella Knowler (BSc Genetics Undergraduate, University of Manchester)

Approach to Vernakalent

June 20, 2014

We recently posted on the power of enzymes for effecting Dynamic Kinetic Resolution reactions. Another impressive example of DKR via transamination has been published by the Process Chemistry group at Merck  (Limanto, J. Ashley, E. R.; Yin, J.; Beutner, G. L.; Grau, B. T.; Kassim, A. M.; Kim, M. M.; Klapars, A.; Liu, Z.; Strotman,... Read More

Greg Hughes (VP Alliance & New Product Development)

Green Make-up

June 12, 2014

The world we live in sees an ever-increasing demand for cosmetics. Central Europe alone is predicted to have a 2.8% growth rate increase in 2014 with a further predicted development pace of 4-5% in following years. In other regions, such as India, the world of cosmetics is set to take off with exponential growth in... Read More

James Nuttall (Former Research Scientist)

Why is the mutated form of the LovD enzyme, more efficient in the synthesis of the drug simvastatin than the wild-type LovD?

May 27, 2014

Why is the mutated form of the LovD enzyme, more efficient in the synthesis of the drug simvastatin than the wild-type LovD? Last month scientists at the University of California-Los Angeles (UCLA) and Codexis published a paper in Nature Chemical Biology entitled: The role of distant mutations and allosteric regulation on LovD active site dynamics.... Read More

Gjalt Huisman (VP Program Manager, Pharmaceuticals department)

Rx-360 Celebrates 5 Years of Protecting Patient Safety

May 8, 2014

Rx-360 is celebrating its 5th anniversary with a special one-day Conference in Washington, DC, on Thursday June 5th 2014. The conference will focus on Supply Chain Security and Supplier Quality, and takes place directly after the 2014 PDA/FDA Pharmaceutical Supply Chain Conference at the JW Marriott Washington DC Hotel. The program kicks off with a... Read More

Scott Watson (VP, Sales & marketing)

AIChE NorCal Process Development Symposium

April 21, 2014

Event: AIChE NorCal Process Development Symposium When: Thursday May 1st, 2014 Where: Palo Alto, CA USA Website: http://www.aiche.org/conferences/norcal-process-development-symposium/2014/2014-norcal-process-development-symposium-contacts More detailed technical program is at: http://www.aiche.org/conferences/norcal-process-development-symposium/2014/events Why should participants attend? Successful process development is necessary for all projects to successfully transition from concept to commercialization.  The Organizing Committee has come up with a program featuring ten... Read More

Cawas Cooper (Senior Project Manager )

World Orphan Drug Congress 2014

April 18, 2014

North America’s Largest Commercially-focused Orphan Drug Event Check out their website here: http://www.terrapinn.com/2014/world-orphan-drug-congress-usa/index.stm Excerpt from website: About the event The 4th annual World Orphan Drug Congress USA is where industry, government and payers come to develop new strategies and partnerships to advance orphan drug development and patient access. This is the largest, global event that stakeholders go... Read More

Scientist at Codexis (Scientist)

Biochemistry Scientist at Codexis

The Power of Biocatalysis

March 21, 2014

The Power of Biocatalysis Biocatalysis brings sophisticated new approaches to synthetic chemistry that will significantly advance innovation, development and manufacturing processes in diverse application areas. These areas include, but are not limited to, fine chemicals, advanced pharmaceutical intermediates, agrochemicals, feed stocks, food ingredients, detergents components, and biofuels (See, Table 1). For all of these industries,... Read More

Greg Hughes (VP Alliance & New Product Development)

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